diff --git a/swh/core/api/serializers.py b/swh/core/api/serializers.py
--- a/swh/core/api/serializers.py
+++ b/swh/core/api/serializers.py
@@ -56,6 +56,7 @@
     (PagedResult, "paged_result", _encode_paged_result),
     # Only for JSON:
     (bytes, "bytes", lambda o: base64.b85encode(o).decode("ascii")),
+    (Exception, "exception", lambda e: exception_to_dict(e)),
 ]
 
 DECODERS = {
diff --git a/swh/core/api/tests/test_rpc_client_server.py b/swh/core/api/tests/test_rpc_client_server.py
--- a/swh/core/api/tests/test_rpc_client_server.py
+++ b/swh/core/api/tests/test_rpc_client_server.py
@@ -30,6 +30,10 @@
     def raise_typeerror(self):
         raise TypeError("Did I pass through?")
 
+    @remote_api_endpoint("raise_exception_chain")
+    def raise_exception_chain(self):
+        raise Exception(Exception("error"))
+
 
 # this class is used on the client part. We cannot inherit from RPCTest
 # because the automagic metaclass based code that generates the RPCClient
@@ -115,3 +119,12 @@
         str(exc_info.value)
         == "<RemoteException 500 TypeError: ['Did I pass through?']>"
     )
+
+
+def test_api_raise_exception_chain(swh_rpc_client):
+    with pytest.raises(RemoteException) as exc_info:
+        swh_rpc_client.post("raise_exception_chain", data={})
+
+    assert exc_info.value.args[0]["type"] == "Exception"
+    assert exc_info.value.args[0]["args"][0][b"swhtype"] == "exception"
+    assert exc_info.value.args[0]["args"][0][b"d"]["exception"]["message"] == "error"